Short Summary: A mind-bending dive into evolutionary biology and health through a biophysicist’s lens, with Dr. Jack Kruse delivering provocative insights about biology, medicine, and health.
About the guest: Jack Kruse, MD, is a neurosurgeon known for integrating biophysics into medicine. He challenges conventional biochemistry with his “leptin prescription” and decentralized health approach.
Note: Podcast episodes are fully available to paid subscribers on the M&M Substack and everyone on YouTube. Partial versions are available elsewhere. Full transcript and other information on Substack.
Episode Summary: Dr. Jack Kruse joins host Nick Jikomes to explore the Great Oxygenation Event’s role in shaping life, linking it to modern health via biophysics over biochemistry. They discuss oxygen’s impact on metabolism, the significance of deuterium-depleted water, and sunlight’s influence on the leptin-melanocortin pathway. Kruse shares his dramatic weight loss journey using sunlight and cold therapy, critiques modern tech-driven obesity, and unveils a controversial history of SV40 in vaccines, tying it to cancer spikes.
Key Takeaways:
The Great Oxygenation Event (2.1-2.4 billion years ago) drove life’s shift to oxygen-based metabolism, with cyanobacteria as key players.
Kruse argues biophysics, not biochemistry, explains evolution, spotlighting light as life’s fundamental driver.
Deuterium-depleted water is important for enabling our cells and mitochondria to use energy from the TCA cycle without “shocking” the body.
Sunlight exposure boosts nitric oxide, reducing food needs via the leptin pathway, challenging diet norms.
Kruse lost 133 pounds in 11 months using sunlight and cold therapy, inspiring his “leptin prescription.”
He links obesity to indoor tech lifestyles, disrupting heme proteins and mitochondrial function.
SV40, a virus in 1950s polio vaccines, may connect to cancer rises, a story Kruse says was buried by centralized science.
Related episode:
M&M #196: Vaccine Contamination & Fiat Science | Kevin McKernan
*Not medical advice.
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Episode transcript below.
Episode Chapters:
00:00:00 Intro
00:05:40 Evolutionary Mysteries
00:10:07 Great Oxygenation Event
00:15:33 Oxygen & Metabolism
00:20:01 Paramagnetism & Nitric Oxide
00:25:41 DHA & Leptin Pathways
00:30:48 Mitochondrial Protection
00:35:01 Deuterium-Depleted Water
00:40:00 Sunlight & Health
00:45:00 Obesity Epidemic
00:50:00 Jack’s Weight Loss Journey
00:55:00 Leptin Prescription
01:00:00 SV40 & Vaccines
01:05:00 Cancer Spike Revelations
Full AI-generated transcript below. Beware of typos & mistranslations!
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