Nick talks to biochemist Jospeh Baur, PhD, whose lab at the University of Pennsylvania studies the molecular mechanisms of aging and metabolism. These discuss: aging as a passive vs. regulated process; mechanisms of aging (DNA mutations, oxidative stress, etc.); NAD and its role in normal physiology; the biology of sirtuins; rapamycin as an immunosuppressant & modulator of aging; the effects of diet & caloric restriction on aging; the potential slowing and reversing aging, and more.
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Aging, Metabolism, Caloric Restriction, NAD, Resveratrol, Rapamycin, Sirtuins, Longer Life | Joe Baur | #64