Jan 12 • 1HR 15M

Biochemistry & Molecular Biology of Serotonin Receptors, Tryptamines & Psychedelics | Ryan Gumpper | #102

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Nick Jikomes
Whether food, drugs or ideas, what you consume influences who you become. Learn directly from the best scientists & thinkers about how your body & mind react to what they're fed. New episodes weekly. Not medical advice.
Episode details

Nick talks to biochemist & biophysicist Dr Ryan Gumpper, a postdoc in Dr. Bryan Roth's lab at the University of North Carolina. They discuss the biochemistry, molecular biology & biophysics of serotonin receptors, including the molecular details for what happens when serotonin and tryptamines psychedelics (e.g. LSD) bind to 5HT2A receptors in the brain. They also discuss how understand these details relates to the quest to discover novel psychedelic-derived compounds with therapeutic benefits, as well as the inspiration Ryan received from reading Alexander Shulgin's famous book, PIHKAL.

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